Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ic50 data for polymerid = 50004433
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human YSK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  15.6nMAssay Description:Inhibition of human YSK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50:  57nMAssay Description:Inhibition of wild-type human partial length YSK4 (T1019 to H1328 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50579217(CHEMBL4871593)
Affinity DataIC50:  59nMAssay Description:Inhibition of YSK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597760(US11608319, Compound 7)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597761(US11608319, Compound 8)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597766(US11608319, Compound 12)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597767(US11608319, Compound 13)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597765(US11608319, Compound 11)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597773(US11608319, Compound 19)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597768(US11608319, Compound 14)
Affinity DataIC50: >1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50585046(CHEMBL5086263)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of YSK4 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597759(US11608319, Compound 6)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597757(US11608319, Compound 5)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597753(US11608319, Compound 2)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597769(US11608319, Compound 15)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597763(US11608319, Compound 10)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597771(US11608319, Compound 17)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597752(US11608319, Compound 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM597770(US11608319, Compound 16)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50614163(CHEMBL5288779)
Affinity DataIC50:  3.70E+6nMAssay Description:Inhibition of wild type human YSK4 in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed